Gene therapy for cardiovascular disease
- PMID: 11714096
- DOI: 10.1016/s1471-4892(01)00027-3
Gene therapy for cardiovascular disease
Abstract
Cardiovascular gene therapy has progressed to the point where clinical trials are now underway, in particular, for peripheral and myocardial ischemia and for restenosis. The delivery vectors are now more sophisticated--targeted to deliver genes only to specific tissues, and with gene expression regulated by disease-inducible promoters--which contributes to improved safety.
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