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Review
. 2001 Apr;1(2):197-202.
doi: 10.1016/s1471-4892(01)00027-3.

Gene therapy for cardiovascular disease

Affiliations
Review

Gene therapy for cardiovascular disease

K F Kozarsky. Curr Opin Pharmacol. 2001 Apr.

Abstract

Cardiovascular gene therapy has progressed to the point where clinical trials are now underway, in particular, for peripheral and myocardial ischemia and for restenosis. The delivery vectors are now more sophisticated--targeted to deliver genes only to specific tissues, and with gene expression regulated by disease-inducible promoters--which contributes to improved safety.

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