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. 2000 Mar;2(1):61-8.
doi: 10.1053/jfms.2000.0067.

Bartonella spp antibodies and DNA in aqueous humour of cats

M R Lappin  1 , D L Kordick, E B Breitschwerdt
Affiliations

Bartonella spp antibodies and DNA in aqueous humour of cats

M R Lappin et al. J Feline Med Surg. 2000 Mar.

Abstract

Bartonella spp antibodies were measured in the serum and aqueous humour of cats with and without uveitis and polymerase chain reaction (PCR) for Bartonella spp DNA was performed on aqueous humour from most of the cats. Serum and aqueous humour were assayed from 49 client-owned cats with uveitis, 49 healthy shelter cats, and nine cats experimentally inoculated with either B henselae or B clarridgeiae, 454 days after inoculation. An aqueous antibody coefficient (C value) was calculated for cats positive for Bartonella spp antibodies in the aqueous humour. Ocular production of Bartonella spp IgG (C value >1) was detected in seven of 49 cats with uveitis, none of 49 healthy shelter cats, and four of nine experimentally inoculated cats. The organism was detected by PCR in the aqueous humour of three of 24 cats with uveitis, one of 49 healthy shelter cats, and four of nine experimentally inoculated cats. Bartonella spp infect the eyes of some cats following natural exposure or experimental inoculation and may cause uveitis in some cats.

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References

    1. Bergmans AM, Schellekens JFP, van Embden JDA, Schouls LM. (1996) Predominance of two Bartonella henselae variants among cat-scratch disease patients in the Netherlands. Journal of Clinical Microbiology 34, 254–260. - PMC - PubMed
    1. Burney DP, Lappin MR, Dow SW, Potter TA, Lappin MR. (1998) Polymerase chain reaction for the detection of Toxoplasma gondii within aqueous humor of experimentally inoculated cats. Veterinary Parasitology 79, 181–186. - PubMed
    1. Chavkin MJ, Lappin MR, Powell CC, Roberts SM, Parshall CJ, Reif JS. (1992) Seroepidemiologic and clinical observations of 93 cases of uveitis in cats. Progress in Veterinary and Comparative Ophthalmology 2, 29–36.
    1. Chavkin MJ, Lappin MR, Powell CC, Cooper CM, Munana KR, Howard LH. (1994) Toxoplasma gondii-specific antibodies in the aqueous humor of cats with toxoplasmosis. American Journal of Veterinary Research 55, 1244–1249. - PubMed
    1. Chomel BB, Abbott RC, Kasten RW, Floyd-Hawkins KA, Kass PH, Glaser CA, Pedersen NC, Koehler JE. (1995) Bartonella henselae prevalence in domestic cats in California: Risk factors and association between bacteremia and antibody titers. Journal of Clinical Microbiology 33, 2445–2450. - PMC - PubMed

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