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Case Reports
. 1975 Aug;36(2):576-81.
doi: 10.1002/1097-0142(197508)36:2<576::aid-cncr2820360237>3.0.co;2-g.

Ph1-positive megakaryoblastic leukemia

D K Hossfeld, D Tormey, R R Ellison
Case Reports

Ph1-positive megakaryoblastic leukemia

D K Hossfeld et al. Cancer. 1975 Aug.

Abstract

A case of megakaryoblastic leukemia is presented. Megakaryoblastosis and erythrocytic hyperplasia of the bone marrow, thrombocythemia, and hepatosplenomegaly were the essential features; 100% of the marrow-derived metaphases were found to be Ph1-positive. Cytologic and chromosomal findings are compatible with the assumption that all three marrow systems were involved in the leukemic process.

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