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Review
. 2001 Nov 20;32(4):555-6.
doi: 10.1016/s0896-6273(01)00509-8.

Potassium channel mechanics

F J Sigworth  1
Affiliations
Free article
Review

Potassium channel mechanics

F J Sigworth. Neuron. .
Free article

Abstract

What is the moving part that switches an ion channel's current on and off? In this issue of Neuron del Camino and Yellen (2001) exploit scanning cysteine mutagenesis and sulfhydryl reagents to show that the intracellular end of the S6 helices forms a mechanical gate for the Shaker potassium channel.

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