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. 1978;1(1):25-8.
doi: 10.1007/BF01805711.

Diagnosis of the mucopolysaccharidoses using cultured skin fibroblasts and amniotic fluid cells

J Butterworth

Diagnosis of the mucopolysaccharidoses using cultured skin fibroblasts and amniotic fluid cells

J Butterworth. J Inherit Metab Dis. 1978.

Abstract

Assay of alpha-L-iduronidase, heparin sulphamidase, N-acetyl-alpha-D-glucosaminidase, arylsulphatase B, alpha-L-fucosidase, beta-glucuronidase, beta-galactosidase and alpha-D-mannosidase in cultured cells is described. Activities in deficient fibroblast strains are compared to control fibroblast strains. The first case of Sanfilippo B in the United Kingdom is reported. A comparison of enzyme activities in cultured fibroblasts and amniotic fluid cells is made.

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References

    1. J Clin Invest. 1974 Oct;54(4):907-12 - PubMed
    1. Clin Chim Acta. 1975 Feb 22;59(1):93-9 - PubMed
    1. Biochem Biophys Res Commun. 1975 Jan 20;62(2):448-55 - PubMed
    1. Biochem Biophys Res Commun. 1976 Jan 12;68(1):292-8 - PubMed
    1. Arch Biochem Biophys. 1973 Oct;158(2):817-21 - PubMed

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