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Case Reports
. 2001 Nov 27;57(10):1885-8.
doi: 10.1212/wnl.57.10.1885.

Onset of multiple sclerosis associated with anti-TNF therapy

N L Sicotte  1 , R R Voskuhl
Affiliations
Case Reports

Onset of multiple sclerosis associated with anti-TNF therapy

N L Sicotte et al. Neurology. .

Abstract

Therapies aimed at inhibiting tumor necrosis factor (TNF), a proinflammatory cytokine implicated in autoimmune disease are effective, especially for rheumatoid arthritis. We report a patient with new onset MS closely associated with the initiation of anti-TNF therapy for juvenile rheumatoid arthritis. It is possible that the inhibition of TNF triggered MS in this individual.

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