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. 2001 Dec;39(12):4535-40.
doi: 10.1128/JCM.39.12.4535-4540.2001.

Differences in clinical and laboratory diagnostic characteristics of penicilliosis marneffei in human immunodeficiency virus (HIV)- and non-HIV-infected patients

S S Wong  1 , K H Wong, W T Hui, S S Lee, J Y Lo, L Cao, K Y Yuen
Affiliations

Differences in clinical and laboratory diagnostic characteristics of penicilliosis marneffei in human immunodeficiency virus (HIV)- and non-HIV-infected patients

S S Wong et al. J Clin Microbiol. 2001 Dec.

Abstract

We compared the clinical and laboratory features of human immunodeficiency virus (HIV)- and non-HIV-infected patients with penicilliosis marneffei. HIV-infected patients had a higher incidence of fungemia. A total of 85.7% of the HIV-negative patients had underlying diseases including hematologic malignancies or had received therapy with corticosteroids or cytotoxic agents. By a Penicillium marneffei-specific mannoprotein Mp1p enzyme-linked immunosorbent assay, serum antigen titers were found to be higher in HIV-positive patients, whereas serum antibody levels were found to be higher in HIV-negative patients.

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Figures

FIG. 1
FIG. 1
Serum P. marneffei antigen and antibody levels in two HIV-positive patients with culture-documented penicilliosis marneffei over time. Day 0 was the day of the first positive fungal culture. AU, arbitrary units.
FIG. 2
FIG. 2
Serum P. marneffei antigen (Ag) and antibody (Ab) titers in patients with (HIV+) and without (HIV−) HIV infection. A.U., arbitrary units.
See this image and copyright information in PMC

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