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Comment
. 2001 Nov 30;294(5548):1845-7.
doi: 10.1126/science.1067418.

Signal transduction. A new thread in an intricate web

M von Zastrow  1 , K Mostov
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Signal transduction. A new thread in an intricate web

M von Zastrow et al. Science. .

Abstract

Understanding how biochemical pathways are connected in the cell is one of the big challenges facing cell biologists. In a Perspective, von Zastrow and Mostov describe new work that identifies a protein called RGS-PX1 as the linchpin that connects signal transduction activated by G protein-coupled receptors with membrane trafficking events.

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