Review
The left-handed double helical nucleic acids
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- PMID: 11732602
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Review
The left-handed double helical nucleic acids
Acta Biochim Pol.
2001.
Abstract
The conversion of right-handed dsDNA and dsRNA to the left-handed Z-conformation involves a reorganization of the nucleotides relative to each other. This conversion can be facilitated by the tight binding of a Z-conformation-specific protein domain from the editing enzyme dsRNA adenosine deaminase. This may influence the modification of both pre-mRNAs as well as some replicating RNA viruses.
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