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Review
. 2001 Nov 30;107(5):559-62.
doi: 10.1016/s0092-8674(01)00594-3.

Recognizing phosphatidylinositol 3-phosphate

S Misra  1 , G J Miller, J H Hurley
Affiliations
Free article
Review

Recognizing phosphatidylinositol 3-phosphate

S Misra et al. Cell. .
Free article

Abstract

Phosphatidylinositol 3-phosphate directs the endosomal localization of regulatory proteins by binding to FYVE and PX domains. New structures of these domains complexed with the phosphoinositide headgroup show how interactions with phosphate and hydroxyl groups differentiate this lipid from all others.

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