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Comment
. 2001 Dec;108(11):1583-7.
doi: 10.1172/JCI14629.

Caught flat-footed: podocyte damage and the molecular bases of focal glomerulosclerosis

D Kerjaschki  1
Affiliations
Comment

Caught flat-footed: podocyte damage and the molecular bases of focal glomerulosclerosis

D Kerjaschki. J Clin Invest. 2001 Dec.
No abstract available

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Figures

Figure 1
Figure 1
Survey view of a rat glomerular capillary loop. Cell bodies of podocytes (P) extend into the urinary space, while their foot processes attach in a regular, interdigitating pattern. US, urinary space; CL, capillary lumen. ×12,000.
Figure 2
Figure 2
High power view of the basal half of a podocyte attached to the lamina rara externs (LRE) of the glomerular basement membrane. The slit diaphragms (SD) insert laterally into the podocyte cell membrane. Three membrane domains are marked: green indicates the apical cell membrane above the slit diaphragm; blue marks the membrane of the slit diaphragm domain; red indicates the cell membrane at the base, or “sole” of the foot process. LD: lamina densa. ×140,000.
Figure 3
Figure 3
Schematic drawing of a latero-basal portion of a podocyte, similar to the area marked in Figure 2. In this greatly simplified graph, molecules are not drawn to a correct scale or shape. The three membrane domains defined in the preceding figure are marked here with the same color code.
See this image and copyright information in PMC

Comment on

References

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