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Clinical Trial
. 2001 Fall;9(4):346-60.

National Institute of Mental Health Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE): Alzheimer disease trial methodology

L S Schneider  1 , P N Tariot, C G Lyketsos, K S Dagerman, K L Davis, S Davis, J K Hsiao, D V Jeste, I R Katz, J T Olin, B G Pollock, P V Rabins, R A Rosenheck, G W Small, B Lebowitz, J A Lieberman
Affiliations
  • PMID: 11739062
Clinical Trial

National Institute of Mental Health Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE): Alzheimer disease trial methodology

L S Schneider et al. Am J Geriatr Psychiatry. 2001 Fall.

Abstract

The authors describe the development of the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) protocol for Alzheimer disease (AD), a trial developed in collaboration with the National Institute of Mental Health (NIMH), assessing the effectiveness of atypical antipsychotics for psychosis and agitation occurring in AD outpatients. They provide an overview of the methodology utilized in the trial as well as the clinical-outcomes and effectiveness measures that were implemented.

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