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Clinical Trial
. 2001 Dec 7;15(18):2441-4.
doi: 10.1097/00002030-200112070-00012.

Failure to maintain long-term adherence to highly active antiretroviral therapy: the role of lipodystrophy

S Duran  1 , M Savès, B Spire, V Cailleton, A Sobel, P Carrieri, D Salmon, J P Moatti, C Leport; APROCO Study Group
Affiliations
Clinical Trial

Failure to maintain long-term adherence to highly active antiretroviral therapy: the role of lipodystrophy

S Duran et al. AIDS. .

Abstract

In a sample of 277 patients included in the French APROCO cohort study who were initially adherent at follow-up visit 4 months after initiation of a protease inhibitor-containing regimen, 76.4% self-reported at least one lipodystrophy-related symptom and 30.0% failed to maintain adherence behaviour 20 months after enrolment. After multiple adjustment for other related factors, such as younger age, alcohol consumption and poor housing conditions, the number of self-reported lipodystrophy symptoms was independently associated with adherence failure.

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