[Anti-phalloidine activity of the silymarins silybine and disilybine]
- PMID: 1174039
[Anti-phalloidine activity of the silymarins silybine and disilybine]
Abstract
Originating from silybin, a phenylchromanone from Silybum marianum (L.) Gaertn., a dimer -- disilybin -- was prepared. Disilybin exhibits a phalloidin antagonistic activity at least 10 times that of silybin with regards to a dose of the same weight.