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. 2002 Jan;30(1):29-30.
doi: 10.1038/ng803. Epub 2001 Dec 17.

Alternative splicing and genome complexity

David Brett  1 , Heike Pospisil, Juan Valcárcel, Jens Reich, Peer Bork
Affiliations

Alternative splicing and genome complexity

David Brett et al. Nat Genet. 2002 Jan.

Abstract

Alternative splicing of mRNA allows many gene products with different functions to be produced from a single coding sequence. It has recently been proposed as a mechanism by which higher-order diversity is generated. Here we show, using large-scale expressed sequence tag (EST) analysis, that among seven different eukaryotes the amount of alternative splicing is comparable, with no large differences between humans and other animals.

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