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. 1975 Jun;31(6):614-9.
doi: 10.1038/bjc.1975.107.

Lymphoreticular response to a syngeneic rat tumour: gravimetric and histological studies

G R Flannery, H K Muller, R C Nairn
Free PMC article

Lymphoreticular response to a syngeneic rat tumour: gravimetric and histological studies

G R Flannery et al. Br J Cancer. 1975 Jun.
Free PMC article

Abstract

Gravimetric and histological studies of lymphoreticular tissues during growth of a syngeneic squamous cell carcinoma in Wistar rats show that the regional lymph node anergy reported previously in this system is associated with replacement of paracortical small lymphocytes by large blastoid cells. The regional node continued to gain weight throughout the period of anergy and showed no atrophy and minimal necrosis. Over the same period the spleen increased in both weight and cytotoxicity.

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