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Review
. 2002 Jan;46(1):1-11.
doi: 10.1128/AAC.46.1.1-11.2002.

Plasmid-determined AmpC-type beta-lactamases

Alain Philippon  1 , Guillaume Arlet, George A Jacoby
Affiliations
Review

Plasmid-determined AmpC-type beta-lactamases

Alain Philippon et al. Antimicrob Agents Chemother. 2002 Jan.
No abstract available

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Figures

FIG. 1.
FIG. 1.
Dendrogram for chromosomal and plasmid-encoded AmpC β-lactamases, calculated by Clustal X (34) and the neighbor-joining method (73). Branch lengths are proportional to the number of amino acid exchanges. GenBank accession numbers for blaAmpC can be found at http://www.rochester.edu/College/BIO/labs/HallLab/AmpC_Phylo.html
FIG. 2.
FIG. 2.
Comparative genetic organization of plasmid-encoded ampC genes related to the chromosomal β-lactamase gene of C. freundii. Adjacent nucleotide homology is that available for each gene and may be more extensive if carried further.
FIG. 3.
FIG. 3.
Structure of the integron coding for DHA-1 β-lactamase in pSAL-1 and its relationship to genes on the chromosome of M. morganii.
FIG. 4.
FIG. 4.
Comparison of the sequence between common regions of In7, In6, pSAL-1 (DHA-1), pROT (DHA-1), pGC-2 (FOX-4), pMVP-1 (CMY-1), pKPW142 (CMY-8), and pRMOX-1 (MOX-1).
See this image and copyright information in PMC

References

    1. Babini, G. S., F. Danel, S. D. Munro, P. A. Micklesen, and D. M. Livermore. 1998. Unusual tazobactam-sensitive AmpC β-lactamase from two Escherichia coli isolates. J. Antimicrob. Chemother. 41:115–118. - PubMed
    1. Barnaud, G., G. Arlet, C. Danglot, and A. Philippon. 1997. Cloning and sequencing of the gene encoding the AmpC β-lactamase of Morganella morganii. FEMS Microbiol. Lett. 148:15–20. - PubMed
    1. Barnaud, G., G. Arlet, C. Verdet, O. Gaillot, P. H. Lagrange, and A. Philippon. 1998. Salmonella enteritidis: AmpC plasmid-mediated inducible β-lactamase (DHA-1) with an ampR gene from Morganella morganii. Antimicrob. Agents Chemother. 42:2352–2358. - PMC - PubMed
    1. Barnaud, G., R. Labia, L. Raskine, M. J. Sanson-Le Pors, A. Philippon, and G. Arlet. 2001. Extension of resistance to cefepime and cefpirome associated to a six amino acid deletion in the H-10 helix of the cephalosporinase of an Enterobacter cloacae clinical isolate. FEMS Microbiol. Lett. 195:185–190. - PubMed
    1. Bauernfeind, A., Y. Chong, and K. Lee. 1998. Plasmid-encoded AmpC β-lactamases: how far have we gone 10 years after the discovery. Yonsei Med. J. 39:520–525. - PubMed

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