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. 2002 Jan;46(1):229-30.
doi: 10.1128/AAC.46.1.229-230.2002.

Microcin E492 is an unmodified peptide related in structure to colicin V

Anne-Marie Pons  1 , Nathalie Zorn, David Vignon, François Delalande, Alain Van Dorsselaer, Gilles Cottenceau
Affiliations

Microcin E492 is an unmodified peptide related in structure to colicin V

Anne-Marie Pons et al. Antimicrob Agents Chemother. 2002 Jan.

Abstract

The pore-forming microcin E492 was purified by solid-phase extraction and reversed-phase high-pressure liquid chromatography. Its molecular mass was 7,886 Da. The entire 84-amino-acid sequence was determined. There is no postranslational modification in the secreted microcin, and the sequence has homologies with the sequence of the microcin colicin V.

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References

    1. De Lorenzo, V. 1984. Isolation and characterisation of microcin E492 from Klebsiella pneumoniae. Arch. Microbiol. 139:72–75. - PubMed
    1. De Lorenzo, V., and A. P. Pugsley. 1985. Microcin E492, a low-molecular-weight peptide antibiotic which causes depolarization of the Escherichia coli cytoplasmic membrane. Antimicrob. Agents Chemother. 27:666–669. - PMC - PubMed
    1. Håvarstein, L. S., H. Holo, and I. F. Nes. 1994. The leader peptide of colicin V shares consensus sequences with leader peptides that are common among peptide bacteriocins produced by gram-positive bacteria. Microbiology 140:2383–2389. - PubMed
    1. Lagos, R., M. Wilkens, C. Vergara, X. Cecchi, and O. Monasterio. 1993. Microcin E492 forms ion channels in phospholipid bilayer membranes. FEBS Lett. 321:145–148. - PubMed
    1. Lagos, R., J. E. Villanueva, and O. Monasterio. 1999. Identification and properties of the gene encoding microcin E492 and its immunity protein. J. Bacteriol. 181:212–217. - PMC - PubMed

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