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Case Reports
. 1975 Oct;36(4):1305-8.
doi: 10.1002/1097-0142(197510)36:4<1305::aid-cncr2820360417>3.0.co;2-#.

Regression of pulmonary metastatic disease associated with intralesional BCG therapy of intracutaneous melanoma metastases

M J Mastrangelo, R E Bellet, J Berkelhammer, W H Clark Jr
Case Reports

Regression of pulmonary metastatic disease associated with intralesional BCG therapy of intracutaneous melanoma metastases

M J Mastrangelo et al. Cancer. 1975 Oct.

Abstract

A 77-year-old white man with 64 intracutaneous melanoma metastases and a pulmonary metastatic deposit was treated with immunotherapy. Over an 8-month period, 17 intracutaneous lesions were inoculated with BCG. All 17 injected lesions and all 47 uninjected intracutaneous lesions resolved; no new nodules appeared and the pulmonary metastasis regressed (greater than 50%). This is the first documented case of a pulmonary metastatic focus responding to intralesional BCG therapy of intracutaneous metastases.

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