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. 2002 Jan;49(1):169-72.
doi: 10.1093/jac/49.1.169.

Plasmid-mediated TEM-3 extended-spectrum beta-lactamase production in Salmonella typhimurium in Casablanca

Rajaa AitMhand  1 , Abdelaziz Soukri, Najat Moustaoui, Hamid Amarouch, Naima ElMdaghri, Danielle Sirot, Mohamed Benbachir
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Plasmid-mediated TEM-3 extended-spectrum beta-lactamase production in Salmonella typhimurium in Casablanca

Rajaa AitMhand et al. J Antimicrob Chemother. 2002 Jan.

Abstract

Isolates of extended-spectrum beta-lactamase (ESBL)-producing Salmonella typhimurium were recovered from children admitted to the IbnRochd University Hospital of Casablanca in 1994. These isolates produced TEM-3 as shown by PCR, isoelectric focusing and sequencing. Production of TEM-3 and resistance to gentamicin were encoded by a 10 kb plasmid that could be transferred by conjugation and transformation. This report extends the list of ESBLs produced by S. typhimurium and stresses the need for continuous surveillance of non-typhoidal Salmonella to adapt antibiotic treatment and preventive measures.

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