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. 2002 Jan 1;30(1):163-5.
doi: 10.1093/nar/30.1.163.

PharmGKB: the Pharmacogenetics Knowledge Base

Micheal Hewett  1 , Diane E Oliver, Daniel L Rubin, Katrina L Easton, Joshua M Stuart, Russ B Altman, Teri E Klein
Affiliations

PharmGKB: the Pharmacogenetics Knowledge Base

Micheal Hewett et al. Nucleic Acids Res. .

Abstract

The Pharmacogenetics Knowledge Base (PharmGKB; http://www.pharmgkb.org/) contains genomic, phenotype and clinical information collected from ongoing pharmacogenetic studies. Tools to browse, query, download, submit, edit and process the information are available to registered research network members. A subset of the tools is publicly available. PharmGKB currently contains over 150 genes under study, 14 Coriell populations and a large ontology of pharmacogenetics concepts. The pharmacogenetic concepts and the experimental data are interconnected by a set of relations to form a knowledge base of information for pharmacogenetic researchers. The information in PharmGKB, and its associated tools for processing that information, are tailored for leading-edge pharmacogenetics research. The PharmGKB project was initiated in April 2000 and the first version of the knowledge base went online in February 2001.

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Figures

Figure 1
Figure 1
The flow of data into and out of PharmGKB.
Figure 2
Figure 2
Some of the relationships among data objects in PharmGKB.
See this image and copyright information in PMC

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