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. 2002 Jan 1;30(1):211-3.
doi: 10.1093/nar/30.1.211.

READ: RIKEN Expression Array Database

Affiliations

READ: RIKEN Expression Array Database

Hidemasa Bono et al. Nucleic Acids Res. .

Abstract

READ, the RIKEN Expression Array Database, is a database of expression profile data from the RIKEN mouse cDNA microarray. It stores the microarray experimental data and information, and provides Web interfaces for researchers to use to retrieve, analyze and display their data. The goals for READ are to serve as a storage site for microarray data from ongoing research in the RIKEN mouse encyclopedia project and to provide useful links and tools to decipher biologically important information. The gene information is based mainly on the fully annotated FANTOM database. READ can be accessed at http://read.gsc.riken.go.jp/. READ also provides a search tool [READ integrates gene expression neighbor (RINGENE)] for genes with similarities in expression profiling.

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Figures

Figure 1
Figure 1
The RINGENE search form (left) and its result (right). The similarity in expression profile based on the Pearson’s correlation coefficient is queried. One can enter an arbitrary number (0.75 in this case) and select the tissues one would like to search for. A group of clones that shows the correlation efficient higher than the chosen value was extracted. By clicking the ‘ViewExpression’ button, the expression profile for each clone will be presented as shown in Figure 2.
Figure 2
Figure 2
The expression profile of a clone set in 49 tissues chosen by the RINGENE program. The control for the microarray experiment was the RNA from 17.5 day whole embryos. Red depicts highly expressed genes, whereas green represents low expression. The color bar is shown at the bottom of the figure. Blank entries represent data missing after the PRIM filtration. All the experiments were done in duplicate and the triangles show cases where only a single result was extracted from the duplicates after the filtration.

References

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