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. 2002 Jan 1;30(1):214-7.
doi: 10.1093/nar/30.1.214.

HugeIndex: a database with visualization tools for high-density oligonucleotide array data from normal human tissues

Peter M Haverty  1 , Zhiping Weng, Nathan L Best, Kenneth R Auerbach, Li-Li Hsiao, Roderick V Jensen, Steven R Gullans
Affiliations

HugeIndex: a database with visualization tools for high-density oligonucleotide array data from normal human tissues

Peter M Haverty et al. Nucleic Acids Res. .

Abstract

High-density oligonucleotide arrays are a powerful tool for uncovering changes in global gene expression in various disease states. To this end, it is essential to first characterize the variations of gene expression in normal physiological processes. We established the Human Gene Expression (HuGE) Index database (www.HugeIndex.org) to serve as a public repository for gene expression data on normal human tissues using high-density oligonucleotide arrays. This resource currently contains the results of 59 gene expression experiments on 19 human tissues. We provide interactive tools for researchers to query and visualize our data over the Internet. To facilitate data analysis, we cross-reference each gene on the array with its annotation in the LocusLink database at NCBI.

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Figures

Figure 1
Figure 1
Database schema for the HugeIndex.
Figure 2
Figure 2
Scatter plot of the expression measurements for brain experiment 7 (pons/medulla tissue) versus the average of 10 other brain tissue experiments.
Figure 3
Figure 3
Chart of the expression of the Mac-2 binding protein in 11 histologically normal brain tissue samples. The negative values are a result of showing expression as the difference in the fluorescence measured at two different points (perfect match and mismatch probes). The log was taken on the absolute value of the expression measure. Bar colors indicate absolute expression levels: red, present; blue, absent.
See this image and copyright information in PMC

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