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Comment
. 2001 Dec 18;98(26):14745-7.
doi: 10.1073/pnas.011601598.

Creating a niche in the cytoskeleton: Actin reorganization by a protein kinase

P A Janmey  1
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Comment

Creating a niche in the cytoskeleton: Actin reorganization by a protein kinase

P A Janmey. Proc Natl Acad Sci U S A. .
No abstract available

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Figures

Figure 1
Figure 1
Three types of proteins that form bundles of actin filaments. In addition to specific protein–protein bonds formed by the Top and Middle examples, release of divalent and other small ions (small blue dots) by multivalent cations with surfaces compatible with the actin filament contour also contribute to the stabilization of actin bundles.
Figure 2
Figure 2
Structures formed by three types of F-actin linking proteins. Actin filaments (green lines) are joined at different angles by proteins that form links with various degrees of flexibility. Note that although the shapes of filamin A and Arp2/3 are based on electron micrographs, their sizes are not drawn to scale. Then contour length of filamin A is near 180 nm, whereas the length of the Arp2/3 complex is ≈10 nm. The dimensions of Arg are not known, but its molecular weight is ≈1/3 that of the filamin A dimer. Domains that contact actin filaments are depicted as light green patches.
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