Central nervous system infection during immunosuppression
- PMID: 11754299
- PMCID: PMC2695971
- DOI: 10.1016/s0733-8619(03)00070-7
Central nervous system infection during immunosuppression
Abstract
Suppression of the immune system by human immunodeficiency virus (HIV) infection or immunosuppressive therapy following transplantation increases susceptibility to CNS infection. Examination of the level and type of immunosuppression, in addition to the clinical and radiologic findings at the time of diagnosis can aid the clinician in determining the most likely etiology of infection. This article discusses how suppression of the host immune status modifies the presentation and diagnosis of selected CNS infections and the recommended treatment for these infections.
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References
-
- Evaluation and management of intracranial mass lesions in AIDS. Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 1998;50:21–26. - PubMed
-
- Practice parameters: Lumbar puncture (summary statement). Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 1993;43:625–627. - PubMed
-
- Adair JC, Call GK, O’Connell JB, Baringer JR. Cerebrovascular syndromes following cardiac transplantation. Neurology. 1992;42:819–823. - PubMed
-
- Amlie-Lefond C, Kleinschmidt-DeMasters BK, Mahalingam R, et al. The vasculopathy of varicella-zoster virus encephalitis. Ann Neurol. 1995;37:784–790. - PubMed
-
- Ammassari A, Cingolani A, Pezzotti P, et al. AIDS-related focal brain lesions in the era of highly active antiretroviral therapy. Neurology. 2000;55:1194–1200. - PubMed
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