doi: 10.1021/np010247p.
Cytotoxic polyacetylenic alcohols from the marine sponge Petrosia species
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- PMID: 11754614
- DOI: 10.1021/np010247p
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Cytotoxic polyacetylenic alcohols from the marine sponge Petrosia species
J Nat Prod.
2001 Dec.
Abstract
New polyacetylenic alcohols (1-5) have been isolated as cytotoxic principles from the marine sponge Petrosia sp. The compounds were particularly cytotoxic against a human melanoma cell line (SK-MEL-2). The gross structures were established on the basis of NMR and MS data, and the absolute configuration was determined by the modified Mosher's method.
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