Review
doi: 10.1016/s1286-4579(01)01494-0.
Salmonella typhimurium outer membrane remodeling: role in resistance to host innate immunity
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- PMID: 11755422
- DOI: 10.1016/s1286-4579(01)01494-0
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Review
Salmonella typhimurium outer membrane remodeling: role in resistance to host innate immunity
Microbes Infect.
2001 Nov-Dec.
Free article
Abstract
Resistance to innate immunity is essential for salmonellae pathogenesis. The salmonellae PhoP/PhoQ regulators sense host environments to promote remodeling of the bacterial envelope. This remodeling includes enzymes that modify lipopolysaccharide (LPS). Modified LPS promotes bacterial survival by increasing resistance to cationic antimicrobial peptides and by altered host recognition of LPS.
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