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Case Reports
. 2001 Nov;43(11):993-6.
doi: 10.1007/s002340100617.

Brain PET and technetium-99m-ECD SPECT imaging in Lhermitte-Duclos disease

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Case Reports

Brain PET and technetium-99m-ECD SPECT imaging in Lhermitte-Duclos disease

K Ogasawara et al. Neuroradiology. 2001 Nov.

Abstract

Two patients with Lhermitte-Duclos disease were evaluated by brain positron emission tomography (PET) and technetium-99m-ethyl cysteinate dimer (99mTc-ECD) single-photon emission computed tomography (SPECT). In the lesions in both patients, hyperperfusion was detected on cerebral blood flow images obtained by PET, and hyperactivity by standard 99mTc-ECD SPECT. Dynamic 99mTc-ECD SPECT images demonstrated a plateau of activity in each lesion. These findings suggest that lesions in Lhermitte-Duclos disease have a retention mechanism for 99mTc-ECD equivalent to that of normal neural tissue.

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