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. 1975 Sep 10;29(2):127-34.
doi: 10.1007/BF00430349.

The human leukocyte test system. VI. The use of sister chromatid exchanges as possible indicators for mutagenic activities

The human leukocyte test system. VI. The use of sister chromatid exchanges as possible indicators for mutagenic activities

B Beek et al. Humangenetik. .

Abstract

The trifunctional alkylating chemical mutagen trenimon increases the frequency of sister chromatid exchanges in human leukocyte chromosomes in vitro, as revealed by a BUdR-Giemsa method. Treatment with lead acetate exhibited negative results in this respect. The use of sister chromatid exchanges as possible indicators for mutagenic activities is discussed.

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