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. 1975 Sep 10;29(2):127-34.
doi: 10.1007/BF00430349.

The human leukocyte test system. VI. The use of sister chromatid exchanges as possible indicators for mutagenic activities

B Beek, G Obe

The human leukocyte test system. VI. The use of sister chromatid exchanges as possible indicators for mutagenic activities

B Beek et al. Humangenetik. .

Abstract

The trifunctional alkylating chemical mutagen trenimon increases the frequency of sister chromatid exchanges in human leukocyte chromosomes in vitro, as revealed by a BUdR-Giemsa method. Treatment with lead acetate exhibited negative results in this respect. The use of sister chromatid exchanges as possible indicators for mutagenic activities is discussed.

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