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Clinical Trial
. 2000 Sep;13(Spec No):5C-10C.

Essential oils in an antiplaque and antigingivitis dentifrice: a 6-month study

Affiliations
  • PMID: 11763912
Clinical Trial

Essential oils in an antiplaque and antigingivitis dentifrice: a 6-month study

J Coelho et al. Am J Dent. 2000 Sep.

Abstract

Purpose: To determine if a dentifrice formulated with the fixed combination of essential oils possessed antiplaque and antigingivitis properties.

Materials and methods: This study was a blinded, randomized, controlled clinical trial. The 6-month study had clinical examinations at baseline, 3 and 6 months. The examinations consisted of three indices; a plaque index, the Modified Gingival Index and a bleeding index.

Results: At 6 months, the essential oil-containing dentifrice group had statistically significantly (P < 0.001) lower whole-mouth and interproximal mean plaque index scores exhibiting mean reductions of 18.3% and 18.1% relative to the vehicle control. At 6 months, the essential oil-containing dentifrice group had statistically significantly (P < 0.001) lower whole-mouth and interproximal mean gingival index scores compared to the vehicle control with reductions of 16.2% and 15.5%, respectively. Finally, for the gingival bleeding index, the essential oil-containing dentifrice group had statistically significantly (P < 0.001) lower whole-mouth and interproximal mean bleeding index scores and reductions of 40.5% and 46.9% at 6 months compared to the vehicle control.

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