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Comparative Study
. 1975 Sep;2(3):218-21.
doi: 10.1128/jcm.2.3.218-221.1975.

Evaluation of an indirect hemagglutination test for the diagnosis of human leptospirosis

C R Sulzer, J W Glosser, F Rogers, W L Jones, M Frix
Comparative Study

Evaluation of an indirect hemagglutination test for the diagnosis of human leptospirosis

C R Sulzer et al. J Clin Microbiol. 1975 Sep.

Abstract

A presumptive hemagglutination test for the serological diagnosis of leptospirosis in humans is described. The antigen was prepared from a soluble alcohol extract of an andamana strain sorbed to human O-negative erythrocytes and preserved by pyruvic aldehyde fixation. In this study, the overall sensitivity of the hemagglutination test was 92% in contrast to 69% for the presumptive slide agglutination test. The specificity was 95% for the hemagglutination test in comparison with 83% for the slide test.

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