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Review
. 2000 Jun;32(3):269-75.
doi: 10.1023/a:1005589029959.

NM23/nucleoside diphosphate kinase and signal transduction

A S Otero  1
Affiliations
Review

NM23/nucleoside diphosphate kinase and signal transduction

A S Otero. J Bioenerg Biomembr. 2000 Jun.

Abstract

NM23s (or NDP kinases) regulate a fascinating variety of cellular activities, including proliferation, development, and differentiation. All these processes are modulated by external stimuli, leading to the idea that this family of proteins modulates transmembrane signaling pathways. This review summarizes the evidence indicating that NM23/NDP kinases participate in transmembrane signaling in eukaryotic cells and discusses the molecular mechanisms proposed to account for these actions.

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