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Case Reports
. 2001 Nov;24(6):681-2.
doi: 10.1023/a:1012715110596.

Effect of ramipril in a patient with glycogen storage disease type I and nephrotic-range proteinuria

I Pela  1 , M A Donati, E Zammarchi
Affiliations
Case Reports

Effect of ramipril in a patient with glycogen storage disease type I and nephrotic-range proteinuria

I Pela et al. J Inherit Metab Dis. 2001 Nov.

Abstract

We studied the effect of ramipril on urinary protein excretion and arterial pressure in a 27-year-old patient with GSD Ia and heavy proteinuria (2-3 g /24 h). Ramipril therapy resulted in an important reduction of proteinuria (0.3-0.5 g/24 h): no changes were observed in arterial pressure and renal function during the 12-month follow-up. We conclude that treatment with ramipril can be employed effectively and safely in GSD Ia patients with nephrotic-range proteinuria.

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References

    1. J Inherit Metab Dis. 2000 Jul;23(5):459-63 - PubMed
    1. N Engl J Med. 1988 Jan 7;318(1):7-11 - PubMed

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