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. 2001 Oct;30(5):328-31.

[Clinicopathologic features and prognosis of lymphoepithelioma-like carcinoma of the lung]

[Article in Chinese]
A Han  1 , M Xiong, Y Gu, S Lin, M Xiong
Affiliations
  • PMID: 11769726

[Clinicopathologic features and prognosis of lymphoepithelioma-like carcinoma of the lung]

[Article in Chinese]
A Han et al. Zhonghua Bing Li Xue Za Zhi. 2001 Oct.

Abstract

Objective: To analyze the clinicopathologic features and prognosis of lymphoepithelioma-like carcinoma (LELC) of the lung.

Methods: 26 cases of pulmonary LELC with available long-term follow-up information were compared with 84 cases of pulmonary non-LELC(33 cases of squamous cell carcinoma, 36 cases of adenocarcinoma, 6 cases of adeno-squamous carcinoma and 9 cases of large cell carcinoma) with available long-term follow-up information using Kaplan-Meier method and the generalized Wilcoxon test.

Results: LELC of the lung had a better prognosis than non-LELC (P < 0.05). Further study showed that pulmonary LELC had a significantly better prognosis than adeno-squamous carcinoma and large cell carcinoma. However, there was no significant prognostic differences between pulmonary LELC and squamous cell carcinoma and adenocarcinoma. Tumor recurrence and necrosis (> or = 5% of tumor) were associated with poor prognosis.

Conclusion: Pulmonary LELC, which is a very rare and unique entity, has a better prognosis after therapy.

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