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. 2001 Nov;30(4):277-9.
doi: 10.1024/0301-1526.30.4.277.

Impaired venous hemodynamics in a minority of patients with chronic leg ulcers due to sickle cell anemia

H Chalchal  1 , W Rodino, S Hussain, I Haq, T Panetta, W Solomon, P Gillette, A S Braverman
Affiliations

Impaired venous hemodynamics in a minority of patients with chronic leg ulcers due to sickle cell anemia

H Chalchal et al. Vasa. 2001 Nov.

Abstract

Background: Chronic or recurrent leg ulceration occurs in 25% of sickle cell anemia patients, but not in the remaining 75%. Doppler studies of venous function were normal in 16 sickle cell anemia patients with leg ulcers.

Patients and methods: Venous Duplex Ultrasound was used to study 33 sickle cell anemia patients with chronic leg ulcers.

Results: Six of the 33 patients had venous reflux in at least one leg.

Conclusions: Venous insufficiency may contribute to the development of leg ulcers in a minority of sickle cell anemia patients. A minority of sickle cell anemia patients with chronic leg ulcers can be shown to have leg venous reflux by duplex ultrasound imaging.

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