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Clinical Trial
. 2002 Jan;159(1):143-5.
doi: 10.1176/appi.ajp.159.1.143.

Stress management and immune system reconstitution in symptomatic HIV-infected gay men over time: effects on transitional naive T cells (CD4(+)CD45RA(+)CD29(+))

Michael H Antoni  1 , Dean G Cruess, Nancy Klimas, Kevin Maher, Stacy Cruess, Mahendra Kumar, Susan Lutgendorf, Gail Ironson, Neil Schneiderman, Mary Ann Fletcher
Affiliations
Clinical Trial

Stress management and immune system reconstitution in symptomatic HIV-infected gay men over time: effects on transitional naive T cells (CD4(+)CD45RA(+)CD29(+))

Michael H Antoni et al. Am J Psychiatry. 2002 Jan.

Abstract

Objective: Changes in immunologic status were evaluated in 25 HIV-infected men randomly assigned to a 10-week stress management intervention or a wait-list control condition.

Method: The authors monitored changes in number of transitional naive T cells (CD4(+)CD45RA(+)CD29(+)) over 6-12 months after the completion of the intervention.

Results: Men receiving stress management had higher CD4(+) CD45RA(+)CD29(+) cell counts at follow-up than did the control subjects. This difference was independent of initial number of naive T cells and HIV virus load.

Conclusions: Stress management is associated with immunologic reconstitution in HIV-positive gay men.

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