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. 2002 Jan;40(1):281-3.
doi: 10.1128/JCM.40.1.281-283.2002.

Evaluation of a strand displacement amplification assay (BD ProbeTec-SDA) for detection of Neisseria gonorrhoeae in urine specimens

Deniz Akduman  1 , Josephine M Ehret, Kimberly Messina, Sharron Ragsdale, Franklyn N Judson
Affiliations

Evaluation of a strand displacement amplification assay (BD ProbeTec-SDA) for detection of Neisseria gonorrhoeae in urine specimens

Deniz Akduman et al. J Clin Microbiol. 2002 Jan.

Abstract

The performance of a strand displacement amplification assay (the BDProbeTec-SDA assay) in detecting Neisseria gonorrhoeae in urine specimens was evaluated. When performed under stringent quality control conditions, the BDProbeTec-SDA assay is a sensitive, specific, and efficient method for the screening of large numbers of noninvasively obtained specimens. Because the predictive value of an assay is a function of the prevalence of the disease, culture confirmation is needed for samples with positive results from populations in which the prevalence of a disease is low or in situations in which false-positive results may have important medical, psychosocial, or medicolegal consequences.

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