[Analysis of the clinical characteristics and the pathology of large cell lung cancer]
- PMID: 11775810
[Analysis of the clinical characteristics and the pathology of large cell lung cancer]
Abstract
Objective: To study the clinical characteristics and the pathology of large cell lung cancer (LCLC).
Methods: Comparing the microscopic and immunohistochemical findings with clinical data by analyzing 54 cases of surgically treated LCLC from 1978 to 1997.
Results: There were 6 cases of clear cell carcinoma and one case of giant cell carcinoma in 54 cases. Male:female was 5:1(45/9). LCLC accounted for 1.28% of all surgically treated lung cancers. The average survival time was 23 months. The positive rate of P53 protein expression was 65%(13/20). The positive rate of PCNA staining was 100%(20/20).
Conclusions: LCLC may be divided into squamous type, adenomatous type, neuroendocrine type and undifferentiated type.
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