[Analysis of the clinical characteristics and prognostic factors with primary normal-sized epithelial ovarian carcinoma syndrome]

Abstract

Objective: To investigate the clinical characteristics and prognostic factors of the primary normal-sized epithelial ovarian carcinoma syndrome.

Methods: The clinical records and pathologic slides of the 10 patients who satisfied the diagnostic criteria were retrospectively analyzed.

Results: The primary normal-sized epithelial ovarian carcinoma syndrome was detected in approximately 1.92% of the patients with the epithelial ovarian carcinoma. The age of the patients at diagnosis ranged from 43-70 years, with a median age of 57 years. The most common presentations included anorexia, increasing abdominal girth and awareness of abdominal or pelvic mass. During the exploratory laparotomy although we often discovered the diffuse metastasis throughout the abdominal and pelvic cavity, the ovaries both appeared normal size and had a fine granularity on the external surface. The survival time of patients with remained tumors smaller than 2.0 cm was longer than those with remained tumors larger than 2.0 cm, but the Log-rank evaluation indicated chi 2 = 0.61, P > 0.05. The patients who underwent postoperative chemotherapy have been noted to achieve some long-term survival. The median survival time was 20 months.

Conclusion: The results predict that the size of the remained tumors may be one of the important factors to the survival and the disease is sensitive to the postoperative chemotherapy.