GABARAP and GABA(A) receptor clustering
- PMID: 11779472
- DOI: 10.1016/s0896-6273(01)00569-4
GABARAP and GABA(A) receptor clustering
Abstract
Coyle et al. (2002), in this issue of Neuron, reveal the crystal structure for the GABA(A) receptor binding protein, GABARAP. They show GABARAP can switch from a monomer to an extended linear polymer form that may function to assemble microtubules during the intracellular trafficking or postsynaptic clustering of GABA(A) receptors.
Comment on
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Structure of GABARAP in two conformations: implications for GABA(A) receptor localization and tubulin binding.Neuron. 2002 Jan 3;33(1):63-74. doi: 10.1016/s0896-6273(01)00558-x. Neuron. 2002. PMID: 11779480
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