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Review
. 2001 Oct;19(10 Suppl):S28-33.
doi: 10.1016/S0167-7799(01)01797-8.

BIA-MS-MS: biomolecular interaction analysis for functional proteomics

T Natsume  1 , H Nakayama, T Isobe
Affiliations
Review

BIA-MS-MS: biomolecular interaction analysis for functional proteomics

T Natsume et al. Trends Biotechnol. 2001 Oct.

Abstract

One of the experimental processes of functional proteomics is the analysis of protein interaction. Here, we review a new analytical platform, BIA-MS, for protein interaction analysis. BIA-MS is an integration of a surface plasmon resonance biosensor for real-time interaction analysis and mass spectrometry for the subsequent identification of interacting molecules.

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