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Review
. 2002 Jan;109(1):3-6.
doi: 10.1172/JCI14841.

Killing the messenger: new insights into nonsense-mediated mRNA decay

Peter H Byers  1
Affiliations
Review

Killing the messenger: new insights into nonsense-mediated mRNA decay

Peter H Byers. J Clin Invest. 2002 Jan.
No abstract available

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References

    1. Schwarze U, Starman BJ, Byers PH. Redefinition of exon 7 in the COL1A1 gene of type I collagen by an intron 8 splice-donor-site mutation in a form of osteogenesis imperfecta: influence of intron splice order on outcome of splice-site mutation. Am J Hum Genet. 1999; 65:336–344. - PMC - PubMed
    1. Iborra FJ, Jackson DA, Cook PR. Coupled transcription and translation within nuclei of mammalian cells. Science. 2001; 293:1139–1142. - PubMed
    1. Ishigaki Y, Li X, Serin G, Maquat LE. Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20. Cell. 2001; 106:607–617. - PubMed
    1. Maquat LE, Li X. Mammalian heat shock p70 and histone H4 transcripts, which derive from naturally intronless genes, are immune to nonsense-mediated decay. RNA. 2001; 7:445–456. - PMC - PubMed
    1. Cheng J, Belgrader P, Zhou X, Maquat LE. Introns are cis effectors of the nonsense-codon-mediated reduction in nuclear mRNA abundance. Mol Cell Biol. 1994; 14:6317–6325. - PMC - PubMed