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Comment
. 2002 Jan;109(1):17-8.
doi: 10.1172/JCI14780.

The buzz about BAFF

David L Vaux  1
Affiliations
Comment

The buzz about BAFF

David L Vaux. J Clin Invest. 2002 Jan.
No abstract available

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Figures

Figure 1
Figure 1
Two TNF-related ligands, BAFF and APRIL, can bind to three identified and one hypothetical TNF receptor-related receptors. BAFF-R can only be bound by BAFF, an interaction that promotes the survival of peripheral B cells.
See this image and copyright information in PMC

Comment on

References

    1. Moore PA, et al. BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator. Science. 1999; 285:260–263. - PubMed
    1. Schneider P, et al. BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth. J Exp Med. 1999; 189:1747–1756. - PMC - PubMed
    1. Shu HB, Hu WH, Johnson H. TALL-1 is a novel member of the TNF family that is down-regulated by mitogens. J Leukoc Biol. 1999; 65:680–683. - PubMed
    1. Mukhopadhyay A, Ni J, Zhai YF, Yu GL, Aggarwal BB. Identification and characterization of a novel cytokine, THANK, a TNF homologue that activates arpoptosis, nuclear factor-kappa B, and c-Jun NH2-terminal kinase. J Biol Chem. 1999; 274:15978–15981. - PubMed
    1. Cheema GS, Roschke V, Hilbert DA, Stohl W. Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based rheumatic diseases. Arthritis Rheum. 2001; 44:1313–1319. - PubMed

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