Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1975 Aug;2(8):1329-43.
doi: 10.1093/nar/2.8.1329.

m7G5'ppp5'GmptcpUp at the 5' terminus of reovirus messenger RNA

Free PMC article

m7G5'ppp5'GmptcpUp at the 5' terminus of reovirus messenger RNA

M Faust et al. Nucleic Acids Res. 1975 Aug.
Free PMC article

Abstract

In the presence of S-adenosyl methionine the 5' terminal guanosine residue of in vitro synthesized reovirus mRNA becomes methylated at the 2'-OH position. In addition, 7-methyl guanylic acid is condensed covalently at the 5' terminus resulting in the formation of a 5' to 5' triphosphate bridge. Analysis of the 5' terminal sequence of methylated reovirus mRNA revealed that it has the structure m7G5'ppp5'GmpCpUp.

PubMed Disclaimer

Similar articles

Cited by

References

    1. Proc Natl Acad Sci U S A. 1975 Jan;72(1):318-22 - PubMed
    1. Proc Natl Acad Sci U S A. 1975 Mar;72(3):1189-93 - PubMed
    1. Nature. 1975 Jan 31;253(5490):374-5 - PubMed
    1. Proc Natl Acad Sci U S A. 1971 Feb;68(2):505-8 - PubMed
    1. Proc Natl Acad Sci U S A. 1975 Feb;72(2):742-5 - PubMed