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Review
. 2002 Jan;61(1):10-9.
doi: 10.1046/j.1523-1755.2002.00086.x.

Toward an etiological classification of developmental disorders of the kidney and upper urinary tract

Martin Pohl  1 , Vibha Bhatnagar, Stanley A Mendoza, Sanjay K Nigam
Affiliations
Free article
Review

Toward an etiological classification of developmental disorders of the kidney and upper urinary tract

Martin Pohl et al. Kidney Int. 2002 Jan.
Free article

Abstract

Toward an etiological classification of developmental disorders of the kidney and upper urinary tract. There are a large number of developmental disorders and syndromes that affect the kidney and upper urinary tract. These have generally been classified according to morphological criteria established decades ago. Although these classifications have been useful, they are incomplete, including some developmental disorders while excluding others. Here, basic cellular and molecular biology studies of kidney and upper urinary tract development in both rodents and humans are utilized to suggest the basis of a new etiologic, if still tentative, classification scheme. This classification may help to identify candidate genes for human diseases by correlating morphology with pathogenetic mechanisms.

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