Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2001 Dec;65(6):747-53.
doi: 10.4269/ajtmh.2001.65.747.

The appearance of a second genotype of Japanese encephalitis virus in the Australasian region

A T Pyke  1 , D T Williams, D J Nisbet, A F van den Hurk, C T Taylor, C A Johansen, J Macdonald, R A Hall, R J Simmons, R J Mason, J M Lee, S A Ritchie, G A Smith, J S Mackenzie
Affiliations

The appearance of a second genotype of Japanese encephalitis virus in the Australasian region

A T Pyke et al. Am J Trop Med Hyg. 2001 Dec.

Abstract

In mid-January 2000, the reappearance of Japanese encephalitis (JE) virus activity in the Australasian region was first demonstrated by the isolation of JE virus from 3 sentinel pigs on Badu Island in the Torres Strait. Further evidence of JE virus activity was revealed through the isolation of JE virus from Culex gelidus mosquitoes collected on Badu Island and the detection of specific JE virus neutralizing antibodies in 3 pigs from Saint Pauls community on Moa Island. Nucleotide sequencing and phylogenetic analyses of the premembrane and envelope genes were performed which showed that both the pig and mosquito JE virus isolates (TS00 and TS4152, respectively) clustered in genotype I, along with northern Thai, Cambodian, and Korean isolates. All previous Australasian JE virus isolates belong to genotype II, along with Malaysian and Indonesian isolates. Therefore, for the first time, the appearance and transmission of a second genotype of JE virus in the Australasian region has been demonstrated.

PubMed Disclaimer

Publication types

LinkOut - more resources