Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2001:21 Suppl 1:S224-9.
doi: 10.1002/gepi.2001.21.s1.s224.

Quantitative trait loci mapping of serum IgE in an isolated Hutterite population

M Alarcón  1 , R M Cantor
Affiliations

Quantitative trait loci mapping of serum IgE in an isolated Hutterite population

M Alarcón et al. Genet Epidemiol. 2001.

Abstract

Serum immunoglobulin E (IgE) is a quantitative trait associated with asthma. A variance components approach to the analysis of data from a subset of a founder population of Hutterites indicated that over half the variability in IgE levels may be due to genes. Two variance components methods suggest that the genetic model underlying IgE does not consist of a single major gene, but of multiple loci with more modest effects. Both approaches identified putative quantitative trait loci on chromosomes 1 and 21.

PubMed Disclaimer

Publication types

Substances