doi: 10.1021/ol0168263.
Total synthesis of crambescidin 359
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- PMID: 11796044
- DOI: 10.1021/ol0168263
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Total synthesis of crambescidin 359
Org Lett.
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Abstract
[structure: see text] Crambescidin 359 (4), which is the "vessel part" of the pentacyclic guanidine alkaloid ptilomycalin A (1), was synthesized for the first time based upon successive 1,3-dipolar cycloaddition reaction. This synthesis established the absolute stereochemistry of 4.
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