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Review
. 2002 Jan;12(1):32-7.
doi: 10.1016/s1050-1738(01)00144-x.

Calmodulin is a limiting factor in the cell

Anthony Persechini  1 , Paul M Stemmer
Affiliations
Review

Calmodulin is a limiting factor in the cell

Anthony Persechini et al. Trends Cardiovasc Med. 2002 Jan.

Abstract

The total intracellular concentration of calmodulin (CaM) in the cell appears to be significantly below the total concentration of its targets, making it a limiting factor in their regulation. In this review we discuss the ways in which this is likely to impact signaling. A key conclusion is that competition for a limiting pool of CaM enables cross-talk between CaM-dependent signaling pathways.

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